Short- and Long-term Effects of Robot-assisted Plication in Diaphragmatic Paralysis

Launched by UPPSALA COUNTY COUNCIL, SWEDEN · Apr 1, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a surgical procedure called robot-assisted diaphragmatic plication, which aims to help patients who have difficulty breathing due to a condition known as diaphragmatic paralysis. This condition can cause severe symptoms like breathlessness and limits physical activity. The trial will look at how effective this surgery is in improving breathing, physical performance, and overall lung function over both short and long periods of time. Researchers will track patients' progress at five hospitals in Sweden, assessing them before and after the surgery at different intervals up to three years.

To participate, you need to be between 18 and 75 years old and have been experiencing symptoms from diaphragmatic paralysis for at least a year. You’ll be scheduled for the surgery if you meet the criteria and can complete forms in Swedish. The trial is not yet recruiting participants, but if you join, you can expect regular check-ups to monitor your breathing and health after the surgery. This study is important because it will provide more information on the benefits of this minimally invasive surgery, helping doctors better understand how to treat patients with this condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with symptomatic unilateral diaphragmatic paralysis persisting for ≥1 year
• • Patients are scheduled for RATS at thoracic surgery clinics in five Swedish university hospitals (Gothenburg, Linköping, Lund, Umeå, and Uppsala).
• Exclusion Criteria:
• • Inability to complete forms in Swedish
• • Neuromuscular disease as the cause of diaphragmatic paralysis
• • Other significant causes of dyspnea
• • Impaired physical capacity from other causes than diaphragmatic paralysis.