Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Launched by TRUSTEES OF DARTMOUTH COLLEGE · Apr 2, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a new program called Therabot-CALM, which is a chatbot designed to help people who struggle with cannabis use, anxiety, and depression. The main goal of the study is to find out if this chatbot is easy to use and if it can help improve symptoms for individuals dealing with these issues. Researchers want to understand how well the chatbot works for users and whether they find it helpful.

To participate, you need to be at least 18 years old and have a current problem with cannabis use and symptoms of anxiety or depression. You should also have reliable internet access and a device that can run the Therabot-CALM program. If you join, you will fill out a questionnaire, take part in two virtual interviews to share your thoughts on the app's design, and use the chatbot for four weeks, providing feedback in a final interview. This study is not recruiting participants yet, but it aims to gather valuable insights on how technology can support mental health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Is 18 years or older.
• • Meet criteria for current CUD (CUDIT-R\>=12) and MDD (PHQ-9\>=10), and/or GAD (GAD-7\>=10).
• • Have reliable access to the internet and a compatible device for Therabot-CALM.
• • Have willingness and capacity to provide informed consent and commit to participating in all assessments and interventions during the study.
• • Attend the first interview.
• Exclusion Criteria:
• • Moderate to High risk of STBs as determined by the C-SSRS or baseline questionnaires.
• • Current psychosis (as determined by brief psychosis screen).
• • Current participation in another digital mental health intervention.