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Search / Trial NCT06921330

Effect of White Cover and Massage on Bilirubin Levels and Phototherapy Duration in Newborns With ABO Incompatibility Receiving Phototherapy

Launched by KARABUK UNIVERSITY · Apr 3, 2025

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

Abo Incompatibility Newborn Phototherapy White Cover Massage Hyperbilirubinemia

ClinConnect Summary

This clinical trial is investigating how using a white cover and gentle massage can affect bilirubin levels and the length of time newborns with ABO incompatibility need phototherapy. ABO incompatibility occurs when a mother's blood type is incompatible with her baby's, leading to a condition called jaundice, which causes yellowing of the skin. The study aims to find out if these two simple methods can help lower bilirubin levels faster, potentially reducing the time babies spend under phototherapy lights.

To be eligible for this study, newborns need to be full-term (between 37 and 42 weeks of pregnancy), weigh at least 2,500 grams, and be healthy aside from having jaundice. They should also be able to feed normally and not have any serious health issues or skin problems that could interfere with massage. If families agree to participate, they can expect their babies to receive standard care along with the added treatments being studied. This trial is not yet recruiting participants, but it aims to provide valuable insights into improving care for newborns facing jaundice due to ABO incompatibility.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Abo-Incompatibility term babies with a gestational age between 37-42 weeks,
  • Does not have a respiratory, cardiovascular, gastrointestinal or neurological disorder or syndrome that would prevent or complicate oral feeding,
  • Birth weight of 2500 g and above,
  • With phototherapy indication,
  • Do not have any health problems other than neonatal jaundice detected in the prenatal period,
  • Those with a stable health condition,
  • Orally fed,
  • No clinical signs of dehydration,
  • Do not have any skin problems that would prevent baby massage,
  • Newborns with written and verbal informed consent from their families will be included in the study.
  • Exclusion Criteria:
  • Premature,
  • Those with congenital malformations,
  • Those with hyperbilirubinemia requiring exchange transfusion,
  • Those with Rh hemolytic disease,
  • Having a positive culture test (sepsis),
  • Those with glucose-6-phosphate dehydrogenase (G6PD) deficiency,
  • Birth weight below 2500 grams,
  • Those who were referred to another center during the research,
  • Discharged early,
  • Unexpected complications developed during the research,
  • Bronze child syndrome occurs during phototherapy,
  • Newborns who develop a pathology that will prevent or complicate oral feeding will not be included in the study.

About Karabuk University

Karabuk University is a distinguished educational institution located in Turkey, dedicated to advancing scientific research and innovation across various fields, including healthcare. As a clinical trial sponsor, the university plays a pivotal role in facilitating cutting-edge research aimed at improving patient outcomes and contributing to the global body of medical knowledge. With a commitment to ethical standards and rigorous scientific methodology, Karabuk University collaborates with healthcare professionals and researchers to design and implement clinical trials that address pressing health challenges, ultimately striving to enhance treatment options and promote public health initiatives.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported