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Search / Trial NCT06922409

The Effects of Naturalistic Light on Post Stroke Complications Related Brain Areas in Stroke Patients During Admission for Rehabilitation.

Launched by RIGSHOSPITALET, DENMARK · Apr 3, 2025

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Circadian Rhythm Disruption Stroke Post Stroke Depression Post Stroke Fatigue Light Therapy Circadian Light

ClinConnect Summary

This clinical trial is studying how natural sunlight, or "naturalistic light," can help improve issues like depression and fatigue in stroke patients during their rehabilitation. After a stroke, many patients experience significant fatigue (up to 85%) and depression (about 30%), which can greatly impact their recovery and overall quality of life. The researchers believe that exposure to naturalistic light might positively influence brain areas related to these problems, and they will use MRI scans and other tests to look for changes in brain function and health.

To participate, patients should be between 65 and 74 years old and have moderate to severe fatigue or depression. They must also be able to stay in a rehabilitation unit for at least 10 days. Unfortunately, those with severe communication difficulties, certain eye problems, or who are not able to cooperate with the study will not be eligible. If someone joins the trial, they can expect to undergo various assessments, including tests for fatigue and mood, MRI scans, and evaluations of their sleep and cognitive abilities, all while receiving care in an environment with natural lighting.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients scoring moderate-severe fatigue and/or depression OR NO fatigue and/or depressione which are evaluated as candidates for the rehabilitation unit.
  • Exclusion Criteria:
  • GCS \< 15
  • No functioning nervus opticus or retina in both eyes
  • Unable to open both eyes
  • Non communicating patients e.g. severe aphasia (incompetent patients)
  • Unable to cooperate to the physical examinations
  • Less than 10 days of hospitalization in the rehabilitation department
  • Claustrophobia
  • If the sub investigator finds the study participant unfit to conduct the investigations

About Rigshospitalet, Denmark

Rigshospitalet, located in Copenhagen, Denmark, is one of the leading hospitals in Scandinavia and a prominent center for clinical research and innovation. As a key academic institution affiliated with the University of Copenhagen, Rigshospitalet is dedicated to advancing healthcare through rigorous clinical trials and groundbreaking research across various medical disciplines. The hospital’s commitment to excellence is reflected in its multidisciplinary approach, collaboration with international research networks, and focus on improving patient outcomes through evidence-based practices. With state-of-the-art facilities and a team of highly qualified professionals, Rigshospitalet plays a crucial role in translating scientific discoveries into effective treatments and therapies.

Locations

Glostrup, Capital Region, Denmark

Patients applied

0 patients applied

Trial Officials

Anders Sode West, MD, PhD

Principal Investigator

Rigshospitalet Glostrup

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported