Pacemaker-related Tricuspid Regurgitation Progression and Long-term Outcomes

Launched by HAIYAN WANG · Apr 3, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at how tricuspid regurgitation (TR), a condition where the heart's tricuspid valve doesn’t close properly, can worsen in patients who have received a pacemaker. TR can lead to serious heart problems and reduce the quality of life for patients. The study will compare different types of pacing methods to see which ones are better at preventing TR from getting worse and improving long-term health outcomes for patients with heart devices.

To be eligible for this study, participants need to be adults who have had a cardiac device implanted at Qianfoshan Hospital between 2015 and 2025. However, those who already have severe TR or have had surgery for their tricuspid valve before getting the pacemaker, as well as those with certain other heart conditions, will not be included. While the study is not yet recruiting participants, it aims to help doctors better understand how to care for patients at risk of worsening TR after getting a pacemaker.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adult patients
• • 2. Patients with an implantable electronic heart device (CIEDs)
• • 3. The patient underwent pacemaker implantation at Qianfoshan Hospital between 2015 and 2025
• Exclusion Criteria:
• • 1. Patients with severe tricuspid regurgitation or those who have undergone tricuspid valve surgery or interventional treatment prior to pacemaker implantation
• • 2. Patients with severe valvular heart disease, congenital heart disease, or arrhythmias
• • 3. Patients with single-chamber pacemakers or poor images