Diagnostic Accuracy of 3-dimensional Imaging Device on Polyps and Adenomas During Colonoscopy

Launched by XIJING HOSPITAL OF DIGESTIVE DISEASES · Apr 3, 2025

Keywords

ClinConnect Summary

This clinical trial is studying a new 3-dimensional (3D) imaging device that is used during colonoscopy to see if it can better identify and evaluate colorectal polyps and adenomas compared to the traditional 2-dimensional (2D) imaging. The researchers want to find out if the 3D device can help doctors make more accurate decisions about treatment and to ensure the procedure is safe for patients. Participants will undergo a colonoscopy to check for polyps and may have some removed (a procedure called polypectomy) using either the 3D or 2D imaging device. They will be monitored for up to 30 days afterward to check for any side effects related to the procedure.

To be eligible for this trial, participants must be over 18 years old and have been diagnosed with colorectal polyps. However, certain individuals will not be able to join, such as those with serious health issues that make the procedure risky or those who are pregnant. If you decide to participate, you will have the opportunity to help researchers learn more about how to improve the detection and treatment of colon polyps, which could benefit many patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged over 18 years;
• • Endoscopically diagnosed with colorectal polyps;
• • Signing the written informed consent.
• Exclusion Criteria:
• • Patients with mental illness or severe functional disorder who cannot cooperate with colonoscopy;
• • Patients with severe cardiopulmonary insufficiency;
• • Patients with severe coagulation disorders or high bleeding risk (platelets \<50×10⁹/L, INR \>1.5; discontinuation of antithrombotic drugs should follow the 2012 Japanese Guidelines for Gastroenterological Endoscopy in Patients Undergoing Antithrombotic Treatment and the2017 Appendix on Anticoagulants Including Direct Oral Anticoagulants;
• • Patients with severe electrolyte imbalances;
• • Patients with acute peritonitis or suspected intestinal perforation;
• • Patients with severe inflammatory bowel disease/toxic megacolon;
• • Patients with polyposis syndromes (e.g., Peutz-Jeghers syndrome, Cronkhite-Canada syndrome, familial adenomatous polyposis \[FAP\], Lynch syndrome, etc.);
• • Patients with stage 3 or higher hypertension (systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg);
• • Patients with untreated severe abdominal hernia, intestinal obstruction, or advanced colorectal cancer;
• • Patients with intestinal strictures of any cause;
• • Cases requiring only endoscopic submucosal dissection (ESD);
• • Pregnancy and lactation.