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Search / Trial NCT06923163

The Effect of Exercise on Metabolic Alteration

Launched by SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY ,CHINESE ACADEMY OF SCIENCES · Apr 3, 2025

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Metabolic Response Energy Expenditure Energy Compensation

ClinConnect Summary

This clinical trial is exploring how aerobic exercise, like running, can help manage obesity in adults. Researchers want to understand how much energy people use during exercise and why this energy doesn't always match the total energy they burn throughout the day. To find out, they will measure participants' body changes and energy levels before starting the exercise program, immediately after completing it, and again eight weeks later.

People aged 18 and older who lead a sedentary lifestyle and have a body mass index (BMI) of 18.5 or higher may be eligible to join the study. Participants will run under supervision five times a week for 12 weeks and take part in lab sessions to check their health and fitness levels before and after the exercise program. It's important to note that individuals with certain health issues, recent major surgeries, or specific conditions will not be able to participate. This trial aims to gather valuable information on the effectiveness of exercise as a tool for weight management and overall health improvement.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Sedentary individuals
  • BMI ≥ 18.5 kg/m2
  • Exclusion Criteria:
  • Individuals who have undergone major surgery in the past 6 months (excluding tooth extraction);
  • Individuals on long-term medication;
  • Individuals with metabolic and cardiovascular diseases such as diabetes, hypoglycemia, and hypertension;
  • Individuals with exercise-related injuries, including joint diseases and fractures;
  • Individuals diagnosed with infectious diseases such as HIV, tuberculosis, malaria, etc.;
  • Individuals with mental and neurological disorders including anorexia nervosa;
  • Individuals who have attempted weight loss or gain through various methods in the past three months;
  • Individuals in preconception, pregnancy, and lactation periods;
  • Individuals with autism and those with metal implants in their bodies.

About Shenzhen Institutes Of Advanced Technology ,Chinese Academy Of Sciences

The Shenzhen Institutes of Advanced Technology (SIAT), part of the Chinese Academy of Sciences, is a leading research institution dedicated to advancing scientific knowledge and technology across various fields, including biomedical research. SIAT is committed to fostering innovation through interdisciplinary collaboration and state-of-the-art facilities, focusing on the translation of research into practical applications. With a strong emphasis on clinical trials and regulatory compliance, SIAT aims to contribute to the global healthcare landscape by developing novel therapies and solutions that address pressing medical challenges.

Locations

Shenzhen, Guang Dong, China

Patients applied

0 patients applied

Trial Officials

John R Speakman, PhD

Principal Investigator

Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported