Metformin in Safety and Efficacy in Gouty Patients

Launched by MOSTAFA BAHAA · Apr 5, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the use of a medication called metformin to see if it can help patients with gout, a condition that causes severe pain and swelling in the joints. Gout can significantly affect a person's quality of life, leading to difficulties in daily activities. Metformin is commonly used to treat diabetes by helping the body use insulin better, and researchers want to find out if it can also be beneficial for people suffering from gout.

To participate in this trial, individuals must be diagnosed with gouty arthritis based on specific medical criteria. However, there are some people who cannot join, such as those with certain serious health conditions like heart or brain disorders, or those taking specific medications. Participants will be closely monitored throughout the trial to assess how well metformin works for managing their gout symptoms. This trial is not yet recruiting, but it aims to provide valuable information on a potential new treatment option for those struggling with gout.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Gouty patients clinically diagnosed as gouty arthritis based on the American College of Rheumatology/European League Against Rheumatism criteria of gout.
• Exclusion Criteria:
• • Systemic disorders such as cardiovascular, neurological, coronary artery disease.
• • Hypertension, hyperlipidemia, diabetes mellitus, active infections.
• • Other inflammatory or autoimmune diseases.
• • Patients on biologics,
• • Cases with hypersensitivity to metformin and those with impaired liver and kidney functions.