Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis

Launched by CAIRO UNIVERSITY · Apr 6, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different dental treatments for children with a condition called irreversible pulpitis, which means that the nerve inside a tooth is damaged and causing pain. The researchers want to compare two treatments: one is called 3Mixtatin pulpotomy, and the other is called Metapex pulpectomy. Both treatments aim to save the primary molars (the baby teeth) of children aged 4 to 9 years who are experiencing pain due to this condition.

To be eligible for the trial, children must have healthy primary molars that are still vital (meaning they have living tissue) but show signs of irreversible pulpitis, such as pain that comes and goes or worsens with temperature changes. Children with certain issues, like teeth that cannot be saved or serious medical conditions, will not be included in the study. If chosen to participate, families can expect to have their child's dental health carefully monitored, and they will receive either of the two treatments being tested. It's important to note that the trial is not yet recruiting participants, so families will need to wait for the study to start before enrolling.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Children aged from 4 to 9 years with vital primary molars showing signs of irreversible pulpitis.
• • Children with spontaneous pain lasting a few seconds to several hours.
• • Pain is intensified by thermal stimulus and persists after its removal.
• • Pulp hemorrhage after performing access cavity and deroofing of pulp chamber showing reddish pink healthy pulp tissue.
• • Radicular pulp health is verified by achieving hemostasis within eight minutes of compression using a cotton pellet with 5% sodium hypochlorite.
• • Absence of peri-apical or inter-radicular radiolucency, widening of periodontal ligament space, internal or external root resorption.
• Exclusion Criteria:
• • Unrestorable primary molars.
• • Primary molars with uncontrolled pulp hemorrhage or pulp necrosis.
• • Medically compromised patients who have systemic disease.
• • Uncooperative children who refuse treatment.
• • Children whose parents are unwilling to place stainless steel crowns.
• • Children whose parents or caregivers refuse to participate in the study or are unable to attend follow-up visits.