Hand Perfusion and Pulse Oximetry Performance

Launched by MAYO CLINIC · Apr 7, 2025

Keywords

ClinConnect Summary

This clinical trial, titled "Hand Perfusion and Pulse Oximetry Performance," is designed to compare two ways of measuring oxygen levels in the blood. Researchers will look at readings from pulse oximeters, which are devices that clip onto your finger, against actual blood samples taken at the same time from participants. This study aims to ensure that these devices work accurately, especially for people with different skin tones, as there can be differences in how well they perform.

To participate in this study, you need to be a healthy adult (between 18 and 75 years old) who is a non-smoker and has a body mass index (BMI) between 18 and 30. The researchers want to include a balanced number of men and women, as well as individuals with darker skin tones, to better understand how the devices work for everyone. Participants will be recruited from the local community and the Mayo Medical Center, and they should not have any heart or lung diseases or be taking medications that could affect the study results. If you decide to participate, you’ll help improve the accuracy of oxygen level measurements for all patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy adult men and women of all races and ethnic backgrounds recruited from faculty and staff of the Mayo Medical Center and from Rochester, MN and surrounding communities.
• • Equal number of male and female participants to address potential sex differences in physiology.
• • We will intentionally recruit subjects with dark skin because of the issues surrounding accuracy of pulse oximetry and skin tone.
• • Non-smokers
• • BMIs between 18-30 kg·m-2.
• • Female subjects will be non-pregnant.
• • Free of cardiopulmonary diseases or other conditions and/or taking medications that might affect pulse oximeter-based estimates of arterial saturation.
• • All inclusion and exclusion criteria are at the discretion of the Principal Investigator.
• • At least 8 of the subjects will have Fitzpatrick Skin Type of IV to VI.
• Exclusion Criteria:
• • • Children under the age of 18 will not be studied. We will exclude children less than 18 years of age because they are unable to give consent, and because these studies are non-therapeutic.