Effect of Nitroglycerin Hydrogel on Repairing Critical Bone Defects

Launched by MINIA UNIVERSITY · Apr 7, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a special gel containing nitroglycerin on healing serious bone injuries that don't heal on their own, known as critical-sized bone defects. These types of injuries can occur in conditions like bone loss or fractures and often require additional medical intervention. The researchers are exploring how this gel can help improve bone formation by using nitroglycerin, which has been shown to enhance bone growth by promoting the activity of bone-building cells.

To participate in this trial, candidates must be adult animals aged between 3 to 7 months and weigh between 250 to 350 grams. The study is not yet recruiting participants, but once it begins, those eligible can expect to receive the nitroglycerin gel applied to their bone injuries and be closely monitored for improvements in healing. This research could potentially lead to better treatments for significant bone injuries in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All animals were adult with an age ranging between 3 to 7 months and a weight ranging between 250 and 350 g
• Exclusion Criteria:
• • other than inclusion