Intraocular Gas Tamponade for Treatment of Large Idiopathic Macular Holes
Launched by THE FILATOV INSTITUTE OF EYE DISEASES AND TISSUE THERAPY · Apr 14, 2025
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
The project is a randomized clinical trial with a follow up time of 6 months comparing the effects of surgical treatment of large (410-1000 μm) idiopathic macular holes. Patients are randomized to vitrectomy surgery with internal limiting membrane peeling using perfluoropropane (15% C3F8), sulfur hexafluoride (20% SF6) gas tamponad. Intra- and postoperative complications are registered.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient age 50 or above.
- • Duration of Symptoms ≤ 12 months.
- • Macular holes having a diameter 410-1000 μm.
- • Informed consent.
- Exclusion Criteria:
- • Patients under 50 years of age.
- • A patient who has already undergone treatment (surgery, laser etc.) for any disease of the retina.
- • Traumatic or pediatric macular holes, and associated retinal detachment.
- • History of any retinal disease such as high myopia, retinal dystrophies, central serous retinopathy, retinal vascular diseases, diabetic retinopathy, uveitis etc.
- • Previous history of glaucoma or ocular hypertension.
- • Failure to give informed consent.
About The Filatov Institute Of Eye Diseases And Tissue Therapy
The Filatov Institute of Eye Diseases and Tissue Therapy is a leading research organization dedicated to advancing the field of ophthalmology through innovative clinical trials and therapeutic solutions. With a strong emphasis on the diagnosis and treatment of various eye diseases, the Institute combines cutting-edge technology with a commitment to patient-centered care. Its multidisciplinary team of experts collaborates on pioneering research initiatives aimed at improving visual health and quality of life for patients, while also contributing to the global body of knowledge in eye care and tissue therapy.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Odesa, , Ukraine
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported