Investigational Study to Evaluate the DPP® Syphilis Screen & Confirm Antibody Point-of-care Test (POCT) to Diagnose Infectious Syphilis

Launched by UNIVERSITY OF MANITOBA · Apr 7, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a new test called the DPP® Syphilis Screen & Confirm antibody point-of-care test (POCT) to see how well it can diagnose infectious syphilis. The goal is to compare the results from this quick test to the standard lab tests we usually use for diagnosing syphilis. Researchers want to find out if the POCT can give accurate results right away during a patient’s visit to the clinic, which could help speed up the diagnosis and treatment process.

To participate in this study, you must be at least 18 years old and attending the Nine Circles Community Health Centre for routine sexual health care that requires syphilis testing. This trial will include about 600 participants over a year, and you’ll provide a small blood sample from a fingerstick for the test. After the test, you’ll also fill out a short survey about your experience. It's important to know that if you are experiencing confusion or distress, or if you have had the POCT test in the last 90 days and are not showing any symptoms, you might not be eligible to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Individuals attending the Clinic for routine sexual health care and requiring syphilis testing as part of this care
• • Be able to provide informed consent and are a minimum 18 years of age are eligible for this study
• • Those who had other STIs in the past, or being suspected of having other STIs, are not excluded as long as testing for syphilis is part of the care provided to them
• Exclusion Criteria:
• • Those who, at the discretion of the HCP/Research Nurse, appear intoxicated and/or with extreme distress, or confused, will be excluded
• • Those below the age of 18 years
• • if it has been less than 90 days since their last POCT study visit and they are asymptomatic.