Effect of Bergamot and Plant Sterols Extract on Serum Lipid Profile

Launched by ISTANBUL BILGI UNIVERSITY · Apr 14, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the effects of two natural dietary supplements, bergamot extract and plant sterols, on cholesterol levels in adults with high cholesterol, known as hyperlipidemia. Previous research has shown that these supplements may help lower bad cholesterol (LDL), total cholesterol, and triglycerides while increasing good cholesterol (HDL), which is beneficial for heart health. The trial aims to see how combining these two supplements can improve cholesterol levels in patients, which could provide an alternative to traditional cholesterol-lowering medications that sometimes have unwanted side effects.

To be eligible for the trial, participants should be adults diagnosed with high cholesterol who can take supplements. However, those with certain health conditions like liver or kidney disease, heart problems, or severe allergies will not be able to participate. Throughout the trial, participants can expect to take the supplements and have their cholesterol levels monitored, along with other health indicators. This research could help find new, effective ways to manage cholesterol and support heart health without the drawbacks of some medications.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults individuals who were diagnosed hyperlipidemia
• • Individuals suitable for taking supplement
• Exclusion Criteria:
• • Chronic liver disease,
• • Chronic kidney disease,
• • Heart failure, infarction or cerebrovascular disease,
• • Pregnant and breastfeeding women,
• • Severe psychiatric disorders,
• • Oncological diseases,
• • People using medications that may interact with black seed oil (anticoagulant, antihypertensive, etc.)
• • People using antilipidemic or anticholesterolemic medications in the last 3 months
• • People with citrus allergies
• • People who do not do heavy exercise
• • People using any dietary supplements
• • People with a known history of allergies
• • People who do not regularly consume alcohol
• • People with special dietary requirements