A Preventive Behavioral Intervention for Young Adults With Psychotic Experiences

Launched by MASSACHUSETTS GENERAL HOSPITAL · Apr 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a program called Resilience Training, aimed at helping college students who may be at risk for developing serious mental health issues, such as psychotic disorders, mood disorders, or anxiety disorders. The study is open to young adults aged 18 to 30 who are in their first or second year of college and have reported experiencing some psychotic symptoms. Participants will be randomly assigned to either receive the Resilience Training or not, to see if this program can help prevent the development of more serious mental health conditions.

To participate, students must be enrolled at the college where the trial is taking place and have a score on a specific questionnaire that indicates they are at risk. However, those who are currently receiving treatment for mental health issues, taking certain medications, or have more severe mental health diagnoses won't be eligible. If you join the study, you can expect to learn skills that may help improve your mental well-being, and you'll be contributing to important research that could help others in the future.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • 1. 18-30 years old
• • 2. Enrolled as a first or second year student (i.e., freshman or sophomore) in an undergraduate program at the college or university where the intervention takes place
• • 3. Students who endorse some psychotic experiences (Peter's et al. Delusion Inventory (PDI) score \> 3)
• Exclusion criteria:
• • 1. Inability to provide informed consent
• • 2. Not proficient in English
• • 3. Current self-reported Diagnostic Statistical Manual 5 (DSM-5) diagnosis with active symptoms (such as active psychotic symptoms, current suicidality, serious active alcohol or substance use, marked deterioration in functioning over the prior month) determined by clinical interview with participant, or self-report of a psychiatric diagnosis that necessitates close monitoring or individual therapy and/or inpatient or partial hospitalization
• • 4. Current enrollment in psychological or behavioral health treatment.
• • 5. Current use of psychotropic medications (other than stimulants) prescribed by a physician.
• • 6. A diagnosis of a serious, chronic mental illness as determined by the Mini-International Neuropsychiatric Interview (MINI)