HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Launched by DARTMOUTH-HITCHCOCK MEDICAL CENTER · Apr 9, 2025

Keywords

ClinConnect Summary

The HOBSCOTCH-CA trial is studying a program designed to help improve the quality of life and cognitive abilities of people who have survived brain cancer or brain tumors. This includes various types of brain tumors like low-grade gliomas and meningiomas. The program, called HOBSCOTCH-CA, involves virtual sessions with a certified Cognitive Coach where participants will learn skills like problem-solving and relaxation techniques. Caregivers can also join the study, which aims to support both the patient and their caregiver.

To participate, individuals must be at least 18 years old, have a diagnosis of brain cancer (excluding glioblastoma), and have completed their treatment at least three months prior to joining the study. Participants will be grouped into two: one group starts the program right away, while the other waits three months before starting. Over about six months, they will attend virtual sessions, do homework, and fill out surveys to track their progress. This trial is not yet recruiting, but it offers a valuable opportunity for brain cancer survivors looking for support in managing their cognitive health.

Gender

ALL

Eligibility criteria

• • CA Participants will be referred to the study by their providers (Oncologist) who will be made aware of the study and inclusion/exclusion criteria. Inclusion Criteria 2. - 5. and Exclusion Criteria 1. - 3. will be confirmed by referring providers. Participants who learn about the study here and elsewhere will be instructed on how to confirm their eligibility with their provider.
• Inclusion Criteria for CA Participant:
• • 1. 18 + years
• • 2. Service members, Veterans and civilians with a diagnosis of brain cancer (excluding glioblastoma)
• • 3. Diagnosis of primary brain tumor with expected survival of 2 years or greater (e.g., low-grade glioma, oligodendroglioma, IDH mutant astrocytoma, meningioma) defined as the presence of a primary lesion on neuroimaging (CT or MRI), confirmed by histopathological examination (Note: some patients being treated for meningioma may be treated with radiotherapy without need for initial histopathologic confirmation)
• • 4. Patients undergoing surgical and/or radiation therapy will have completed their treatment at least 3 months prior to being enrolled in trial (Note: patients receiving chemotherapy or other systemic therapy will be included)
• • 5. Stable on all CNS acting medications for one month prior to enrollment
• • 6. Subjective cognitive complaints
• • 7. Literate and proficient in English
• • 8. Internet access for the pre-session and Session 1 of the HOBSCOTCH-CA program; telephone access for sessions 2-8
• Exclusion Criteria for CA Participant:
• • 1. Presence of a neurodegenerative disease (e.g., Alzheimer's disease, Parkinson's disease)
• • 2. Acute psychiatric disorder or substance abuse
• • 3. Patients with glioblastoma (GBM)
• Inclusion Criteria for CA Participant Caregiver:
• • 1. Age 18 +
• • 2. Caregiver to a patient with a confirmed diagnosis of brain cancer/tumor survivor
• • 3. CA Subject has given permission for their caregiver to participate
• • 4. Literate and proficient in English
• • 5. Internet access (for Pre-HOBSCOTCH and Session 1)
• • 6. Telephone access (for Session 8)
• Exclusion Criteria for CA Participant Caregiver:
• • 1. Significant visual impairment precluding reading or writing
• • 2. No reliable telephone or internet access