The Application of Electrical Stimulation in Postoperative Pain Management of Thyroid Surgery

Launched by XIAONAN HUANG · Apr 9, 2025

Keywords

ClinConnect Summary

This trial is testing whether a wrist-and-ankle electrical stimulation device (CMNS6-1) can help reduce pain after thyroid surgery and whether it is safe to use. It compares real device treatment to a placebo/sham device in adults who have thyroid surgery. Researchers will track how much pain people feel using a 0–10 pain scale (lower is better) at several times after surgery, plus changes in inflammatory markers, nausea or vomiting, and a short questionnaire about recovery one day after surgery. The goal is to see if the device improves pain control and overall recovery compared with placebo.

Who can join and what to expect: adults 18 and older who are undergoing thyroid surgery, with a postoperative pain score of 3 or higher, and whose planned operation time is under 4 hours, may be eligible. Exclusions include recent neck/thyroid surgery, pregnancy, skin problems at the treatment sites, implanted devices like a pacemaker, chronic pain, or participating in another trial. If enrolled, you would receive the device immediately after surgery and again about 4 hours later for 30 minutes each session, using specific wrist/ankle points and a gentle, low-current setting. The study is currently enrolling in Shanghai, China, with about 668 participants planned, and may pave the way for future remote monitoring or AI-assisted pain management.

Gender

ALL

Eligibility criteria

• 1. Inclusion Criteria:
• • Be over 18 years of age;
• • The operation time is less than 4 hours;
• • Postoperative VAS pain score ≥3 points ;
• • Clear consciousness, able to answer questions accurately, free speech, no hearing impairment;
• • Informed consent
• 2. Exclusion Criteria:
• • Neck or thyroid surgery within the past ten years;
• • Menstruating, pregnant and lactating females;Those who are not satisfied with blood glucose control;
• • Skin injury or allergy; skin ulceration;
• • Past history of psychiatric disorder that met the diagnostic criteria of Diagnostic and Manual of Mental Disorders, DSM-IV;
• • Upper respiratory tract infection within 2 weeks before surgery;
• • History of implantation of pace or defibrillator;
• • Allergic to gel or intolerant to electrical stimulation;
• • History of chronic pain, pain VAS score 1 at the examination;
• • Use of sedative analgesic drugs for a long time or within 24 hours;
• • Particip in other clinical trials in the past 4 weeks.