Pulmonary Hypertension Inspiratory Training

Launched by UNIVERSITY OF ARIZONA · Apr 16, 2025

Keywords

ClinConnect Summary

This clinical trial, called the "Pulmonary Hypertension Inspiratory Training," is exploring whether a special type of breathing exercise, known as inspiratory muscle strength training (IMST), can help people with pulmonary hypertension (PH). The study will last for six weeks and will look at how this training affects heart and lung pressures, as well as how well participants are able to exercise and perform daily activities.

To join the study, participants need to be between 65 and 74 years old and must have a confirmed diagnosis of pulmonary hypertension. They should also have a scheduled appointment for a clinical check-up related to their PH within the next eight weeks and have had a recent assessment of their condition without any major changes in treatment. However, certain individuals will not be eligible, including current smokers, those with serious heart or lung conditions, or anyone who has had a major health event like a heart attack or stroke recently. If eligible, participants can expect to engage in the training while also undergoing regular assessments of their health related to pulmonary hypertension.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosed with PH defined by clinical guideline criteria
• • Must already be scheduled for a clinical assessment of their PH within 8 weeks of enrolling in the study.
• • Must have undergone an assessment of their PH in the last 18 months with no major changes in PH management or medication within that period.
• Exclusion Criteria:
• • Current smoker or have smoked in the last 10 years
• • Unable or unwilling to undergo routine functional testing of their PH (i.e., 6-minute walk distance).
• * Presence of significant cardiovascular or respiratory conditions other than PH, including but not limited to:
• • Chronic obstructive pulmonary disease
• • Severe asthma
• • Severe ischemic heart disease
• • Left-sided heart failure
• • History of a major cardiovascular event, such as a myocardial infarction or stroke, within the last 6 months
• • Individuals with an implanted pacemaker or other significant cardiac devices
• • History of neurological, respiratory, head and neck, or thoracic surgeries, or conditions such as a collapsed lung or perforated eardrum
• • Pregnant individuals or those actively trying to become pregnant
• • Individuals with any of the following: chronic laryngitis, chronic bronchitis, emphysema, pneumonia, tuberculosis, chronic cough, extremely high blood pressure (\>170/100), neurological problems, scoliosis, organ transplants, HIV or other immunocompromising conditions, or autoimmune disease.