PLADO for Conservative Management of CKD

Launched by LEBANESE AMERICAN UNIVERSITY · Apr 9, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether a special diet called the PLADO diet, which is mostly made up of plants and has low protein, can help reduce a condition called metabolic acidosis in adults with chronic kidney disease (CKD). Metabolic acidosis is a problem that can make CKD worse, so finding effective ways to manage it is important. The trial will compare the PLADO diet to the regular diet commonly recommended for CKD patients to see which one works better and to check if the PLADO diet is safe and affordable.

To participate in the trial, you need to be at least 18 years old and diagnosed with stages 3 to 5 of CKD, among other health criteria. Participants will receive monthly nutrition education sessions about either the PLADO diet or the standard CKD diet for six months, along with monthly clinic visits for checkups and tests. This trial is currently looking for volunteers, and it’s a great opportunity to contribute to research that could help improve dietary options for people with kidney disease.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 18 years and above, having controlled glycemic and blood pressure parameters on treatment, with an established diagnosis of stages 3-5 CKD and an estimated GFR ≤59 ml/min/1.73 m2 stable for at least three months, and with a normal nutritional status as defined by the GLIM criteria, attending the CKD outpatient clinics at LAUMC-RH, willing to undergo the baseline screening and attend the monthly face-to-face visits at the outpatient department at LAUMC-RH.
• Exclusion Criteria:
• • Patients with overt infection, persistent anorexia, vomiting, or diarrhea within the last month, presence of wasting diseases such as cancer, tuberculosis, liver failure, heart failure, and those with serum potassium \>5.5 mEq/L during the past 6 months.