Comparison of Postoperative Analgesic Efficacy of Transversus Abdominis Plane Block (TAP) and Modified Thoracoabdominal Nerve Block (M-TAPA)

Launched by ANKARA ETLIK CITY HOSPITAL · Apr 10, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two methods of pain relief for patients undergoing laparoscopic cholecystectomy, a common surgery to remove the gallbladder due to gallstones. The trial aims to compare the effectiveness of two types of nerve blocks—Transversus Abdominis Plane Block (TAP) and Modified Thoracoabdominal Nerve Block (M-TAPA)—to see which one provides better pain control after the surgery. Both of these nerve blocks help reduce pain and the need for opioids, which can cause unwanted side effects like nausea and constipation.

To be eligible for this trial, participants must be between 18 and 65 years old, in good health (ASA physical status I-III), and have a body mass index (BMI) between 18 and 30. Those who have serious health issues or are pregnant, among other exclusions, will not be able to participate. If you join the trial, you will receive one of the nerve blocks for pain management, and if you choose not to have the nerve block, standard pain relief methods will be used. This study is important because it seeks to find the best way to manage pain after surgery, helping patients recover more comfortably and quickly.

Gender

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Eligibility criteria

• Inclusion Criteria:
• • 18 to 65 years old
• • American Society of Anesthesiologists (ASA) physical status I-II-III
• • Body mass index 18 to 30 kg/m2
• • Elective laparoscopic cholecystectomy surgery
• Exclusion Criteria:
• • Under 18 and over 65
• • ASA score IV and above
• • Advanced co-morbidity
• • History of bleeding diathesis
• • Patient refusing the procedure
• • Chronic opioid or analgesic use
• • Patients who will operate under emergency conditions
• • Block injection site infection
• • Known allergy to local anesthetics
• • Pregnancy