Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI

Launched by EASTERN MEDITERRANEAN UNIVERSITY · Apr 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how different types of exercises can help improve cognitive function in people with Mild Cognitive Impairment (MCI), a condition that affects memory and thinking skills but is not severe enough to be classified as dementia. The researchers want to compare the effects of exercises that involve using both hands, finger movements, and virtual reality (VR) exercises to see which is most effective at boosting brain function and blood flow in the brain.

To participate in this study, individuals must be between 50 and 75 years old and have been diagnosed with MCI by a doctor. They should have certain scores on cognitive tests indicating mild impairment and be able to walk independently. However, people with certain health issues, such as neurological disorders or those who have recently participated in exercise programs, will not be eligible. Participants can expect to engage in various exercise activities designed to enhance their cognitive skills while contributing to important research that could lead to better treatment options for MCI.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Participants who are between 50-75 years of age
• • Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria,
• • Who has the Montreal Cognitive Assessment score between 13-26,
• • Who has the Quick Mild Cognitive Impairment screen score between 48-67,
• • Who has Instrumental Activities of Daily Living Scale score ≥6/8,
• • Who says yes to "Do you have a memory problem?" question,
• • Who can walk independently without using any walking aids
• Exclusion Criteria:
• • Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
• • Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
• • Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)),
• • Who has daltonism and
• • Who attends any exercise program last 6 months will not be included in this study.