How Can Prefabricated Membranes Load Ascorbic Acid Can Curtail Gingival Recession?

Launched by MINIA UNIVERSITY · Apr 17, 2025

Keywords

ClinConnect Summary

This clinical trial is exploring a new treatment for gingival recession, which is when the gum tissue pulls back from the teeth, exposing their roots. This condition can lead to problems like sensitivity and tooth decay. The trial aims to see if prefabricated membranes that contain ascorbic acid (a form of vitamin C) can help improve treatment outcomes for patients with localized gingival recession. The researchers believe that this method could be a good alternative to traditional surgeries that involve taking tissue from the palate, which can be painful and lead to complications.

To participate in the trial, you need to be over 18 years old and have at least two adjacent teeth with specific gum defects. You should also be in good overall health and not a smoker. Unfortunately, pregnant or breastfeeding women, those with certain dental issues, or individuals who have had recent dental treatments will not be eligible. If you join the study, you’ll receive treatment while contributing to important research that could benefit future patients dealing with similar gum issues.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients of both genders with ages more than 18 years.
• • 2. At least two adjacent teeth in maxillary or mandibular anterior sextant with Cairo classification (RT1 or RT 2) labial GR defect.
• • 3. Good general health with no contraindications for periodontal surgery (American Society of Anesthesiologists I).
• • 4. Non-smoker patients.
• Exclusion Criteria:
• • 1. Pregnant and lactating women.
• • 2. Teeth exhibiting pathologic mobility.
• • 3. Mal alignment teeth.
• • 4. Patients under active orthodontic therapy.
• • 5. Periodontal therapy during the last 6 months.
• • 6. Patients received antibiotics or non-steroidal anti-inflammatory drugs six months before the beginning of the study.