Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

Launched by SEATTLE CHILDREN'S HOSPITAL · Apr 14, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a new exercise called high-resistance inspiratory muscle strength training (IMST) to see how it affects young people with Type 2 diabetes (T2D). IMST involves taking 30 strong breaths against a resistance, which only takes about 5 minutes a day. Researchers want to find out if this training can improve heart and kidney function, blood pressure, and other health markers in youth and young adults with T2D over three months.

To participate in this study, you need to be between 14 and 40 years old and have had Type 2 diabetes for at least one year, with a blood sugar level (measured by HbA1C) below 12%. However, if you have had diabetes for more than 18 years, have certain kidney issues, or high blood pressure, you might not be eligible. If you join the study, you will either do the IMST or a similar, non-active training, and researchers will monitor your health changes throughout the trial. This study is not yet recruiting participants, but it offers a simple and short daily activity that could potentially improve health for young people living with diabetes.

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Eligibility criteria

• • Inclusion Criteria: Aged 14-40, have had T2D for a least one year, HbA1C less than 12%.
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• • Exclusion Criteria: Have had type II diabetes for more than 18 years, estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m2 or Albumin-to-creatinine ratio (ACR) greater than 2200mg/g, blood pressure greater than 160/100 mm Hg.
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