Different Injection Speed on Local Anaesthetic Spread of ESPB

Launched by NANJING FIRST HOSPITAL, NANJING MEDICAL UNIVERSITY · Apr 13, 2025

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ClinConnect Summary

This clinical trial is looking at how the speed of injecting local anesthetic affects its spread in a procedure called the erector spinae plane block (ESPB). This block is used to numb an area during a procedure for lung nodules. The researchers want to find out if injecting the anesthetic quickly (in 30 seconds) makes it work differently compared to a slower injection (in 180 seconds).

To be eligible for this trial, participants need to be between 18 and 80 years old, scheduled for a CT-guided lung nodule localization, and have a body mass index (BMI) between 18 and 30. They must also be healthy enough for the procedure, with certain medical classifications. However, people with allergies to the anesthetic, a history of opioid abuse, or specific medical conditions may not qualify. If you join the trial, you can expect to help researchers learn more about the best way to deliver anesthesia to improve patient care during these types of procedures.

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Eligibility criteria

• Inclusion Criteria:
• • Patients scheduled for CT-guided lung nodule localization under local anesthesia will be selected
• • 1. aged 18-80 years
• • 2. BMI 18-30 kg/m²
• • 3. ASA classification I-III
• Exclusion Criteria:
• • 1. Allergy to the study drug or to local anesthetics
• • 2. History of opioid abuse
• • 3. Previous infection at the ESPB or PVB puncture site
• • 4. Peripheral neuropathy
• • 5. Dysfunction of blood coagulation