Reproductive and Mental Health of Patients With Aplastic Anemia

Launched by INSTITUTE OF HEMATOLOGY & BLOOD DISEASES HOSPITAL, CHINA · Apr 13, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the reproductive and mental health of patients with aplastic anemia, a condition where the bone marrow doesn’t produce enough blood cells. While treatments for aplastic anemia have improved survival rates, they can also affect reproductive health. For women, this may lead to irregular periods or difficulties getting pregnant, while men may experience low sperm counts. The trial aims to better understand how these treatments and the disease itself impact reproductive health in patients aged 18 to 40.

If you are diagnosed with aplastic anemia and are between the ages of 18 to 40, you may be eligible to participate. To join, you should be in good enough health to participate in the study and willing to give your consent. Participants will be monitored throughout the trial to assess their reproductive and mental health. This study is important as it seeks to highlight the challenges faced by young patients with aplastic anemia, potentially leading to better care and support in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of AA
• • Male or female, aged 18-40 years
• • ECOG performance status ≤2
• • Willing and able to comply with the requirements for this study and written informed consent
• Exclusion Criteria:
• • Diagnosis of inherited bone marrow failure syndromes
• • Combined with other hematological diseases
• • Chemotherapy-induced bone marrow failure
• • Pregnant or breastfeeding women
• • Subjects with a history of mental illness or severe psychological disorders
• • Subjects with a history of reproductive system cancer (eg, penile cancer, testicular cancer, prostate cancer, ovarian cancer, cervical cancer, vaginal cancer, etc.)
• • Subjects that the investigator believes have other reasons that make them unsuitable for inclusion in this study