Pre-Sleep Creatine Enhances Anaerobic Power in Recreationally Active Females

Launched by ANKARA YILDIRIM BEYAZIT UNIVERSITY · Apr 15, 2025

Keywords

ClinConnect Summary

This clinical trial is studying whether taking creatine, a common sports supplement, before sleep can improve exercise performance and help with muscle recovery in active young women. In this study, female participants aged 18 to 25 who exercise regularly will be randomly assigned to either take 5 grams of creatine or a placebo (a substance with no active ingredients) 30 minutes before bedtime for a week. Researchers will measure how well participants perform in a specific exercise test and will also collect blood samples to check for signs of muscle damage.

To join the trial, women need to be between 18 and 25 years old, active in structured training sessions at least three times a week for the last six months, and have regular menstrual cycles. It's important that they do not have any recent injuries, allergies to creatine, or are not on certain medications. Participants will continue their usual diet and exercise routine throughout the study. This research aims to see if taking creatine at night can help improve performance and speed up recovery after workouts.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Female, aged 18 to 25 years
• • Recreationally active (engaging in structured resistance training 3-4 times per week for the past 6 months)
• • Regular menstrual cycles (used for scheduling purposes)
• • Able and willing to provide informed consent
• • Agreement to maintain normal diet and training routines throughout the study
• Exclusion Criteria:
• • History of musculoskeletal injury affecting lower or upper limbs within the past 6 months
• • Known allergy or intolerance to creatine or maltodextrin
• • Use of performance-enhancing substances or supplements within the last 30 days
• • Use of recovery modalities such as massage, cryotherapy, or compression garments during the study period
• • Current use of anti-inflammatory medication
• • Pregnancy or breastfeeding
• • Inability to comply with study protocol or scheduled assessments