Study of Colorectal Anastomosis Failures With First Sigmoid or Left Colonic Artery Preservation With D3 Lymphadenectomy
Launched by THE BELOOSTROV CLINIC OF HIGH TECHNOLOGIES · Apr 14, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at different surgical techniques for patients with colorectal cancer who need surgery to remove a tumor. Specifically, it compares two methods: one that preserves the first sigmoid artery and another that preserves the left colonic artery during the surgery. The main goal is to see which method leads to fewer complications, particularly leaks at the connection point (anastomosis) of the intestines after surgery. Researchers will track patients' recovery over 30 days after their operation to gather important information about their healing process.
To take part in this study, patients should be at least 18 years old and have a confirmed diagnosis of colorectal cancer that can be surgically treated. They must also be in generally good health, as indicated by specific medical criteria. Participants will receive detailed care and have their health closely monitored, including any side effects after the surgery. Overall, this trial aims to improve surgical outcomes for people undergoing treatment for colorectal cancer.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Signed informed consent form
- • 2. ECOG status is 0-2.
- • 3. Age over 18 years
- • 4. TNM stage according to version VIII T1b-4aN0-2M0 (M1 in case of resectable metastases confirmed by preoperative staging (colonoscopy, chest and abdominal CT).
- • 5. Histologically confirmed adenocarcinoma of the colon, the proximal edge of which is not higher than or equal to 20 cm from the anus
- • 6. Clinical indications for colorectal resection with anastomosis formation
- Exclusion Criteria:
- • 1. Medical or psychiatric reasons affecting the patient's decision to participate in the study
- • 2. Pregnancy or breastfeeding
- • 3. Medical conditions contraindicated for surgery
- • 4. Synchronous or metachronous malignancies
- • 5. Acute intestinal obstruction, bleeding or perforation
- • 6. Preplanned obstructive bowel resection
About The Beloostrov Clinic Of High Technologies
The Beloostrov Clinic of High Technologies is a leading clinical trial sponsor specializing in innovative healthcare solutions and cutting-edge medical research. Committed to advancing patient care, the clinic integrates state-of-the-art technology and rigorous scientific methodologies to conduct trials across various therapeutic areas. With a focus on enhancing treatment efficacy and safety, the Beloostrov Clinic collaborates with healthcare professionals and research institutions to deliver reliable outcomes that contribute to the global medical community. Their dedication to ethical standards and patient-centered approaches ensures that all studies are conducted with the highest level of integrity and respect for participant welfare.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Saint Petersburg, , Russian Federation
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported