How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study
Launched by UNIVERSITY OF AARHUS · Apr 14, 2025
Trial Information
Current as of July 24, 2025
Not yet recruiting
Keywords
ClinConnect Summary
The IMPROVE-HIP Study is a clinical trial aimed at understanding how early detection and treatment of bleeding can help prevent delirium in older patients who have hip fractures. Delirium is a serious condition that affects a person's mental state and can happen after surgery. In this study, researchers want to find out if patients aged 75 and older benefit from receiving quicker treatment for low blood counts caused by bleeding, which may help lower their chances of developing delirium.
To participate in this trial, individuals must have a hip fracture and be able to communicate in Danish. They will undergo blood tests and vital sign checks, and will be monitored for signs of delirium three times a day for the first two days after surgery. If their blood levels drop too low, they will receive blood transfusions. Participants will have follow-up visits at 30 and 90 days to evaluate their memory, quality of life, hospital readmissions, and survival. Please note that the study is not yet recruiting participants.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Hip fracture
- Exclusion Criteria:
- • Pathological hip fracture
- • Periprosthtic fracture
- • Unable to speak or understand Danish
- • Does not wish to recieve blood transfusion
- • If the investigator finds the patient unable to cooperate to the study (e.g. in case of severe dementia and externalizing behaviour)
About University Of Aarhus
The University of Aarhus, a prestigious research institution located in Denmark, is dedicated to advancing medical science through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university fosters an environment that encourages cutting-edge research and the development of novel therapeutic interventions. Committed to ethical standards and patient safety, the University of Aarhus aims to contribute to the global body of medical knowledge while enhancing healthcare outcomes through rigorous scientific inquiry and evidence-based practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Aarhus, Central Denmark Region, Denmark
Herning, Central Denmark Region, Denmark
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported