How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study

Launched by UNIVERSITY OF AARHUS · Apr 14, 2025

Keywords

ClinConnect Summary

The IMPROVE-HIP Study is a clinical trial aimed at understanding how early detection and treatment of bleeding can help prevent delirium in older patients who have hip fractures. Delirium is a serious condition that affects a person's mental state and can happen after surgery. In this study, researchers want to find out if patients aged 75 and older benefit from receiving quicker treatment for low blood counts caused by bleeding, which may help lower their chances of developing delirium.

To participate in this trial, individuals must have a hip fracture and be able to communicate in Danish. They will undergo blood tests and vital sign checks, and will be monitored for signs of delirium three times a day for the first two days after surgery. If their blood levels drop too low, they will receive blood transfusions. Participants will have follow-up visits at 30 and 90 days to evaluate their memory, quality of life, hospital readmissions, and survival. Please note that the study is not yet recruiting participants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Hip fracture
• Exclusion Criteria:
• • Pathological hip fracture
• • Periprosthtic fracture
• • Unable to speak or understand Danish
• • Does not wish to recieve blood transfusion
• • If the investigator finds the patient unable to cooperate to the study (e.g. in case of severe dementia and externalizing behaviour)