CONDUIT™ Anterior Lumbar Interbody Fusion (ALIF) Cage System in Lumbar Degenerative Disease

Launched by UNIVERSITY COLLEGE DUBLIN · Apr 15, 2025

Keywords

ClinConnect Summary

The CONDUIT™ clinical trial is studying a new device designed to help patients with lumbar degenerative disease, a condition that affects the lower back. Specifically, the trial is looking at the CONDUIT ALIF Cage System, which is a special implant used during a surgical procedure called anterior lumbar interbody fusion (ALIF). This study will follow patients who are having this surgery to see how well the device performs and how it works for different types of patients, including those who may be more frail. The goal is to find out if the results from using this new device are similar to those from previous devices that have been used.

To be eligible for this trial, participants need to be at least 18 years old and scheduled for the ALIF procedure where the CONDUIT cage is suitable. However, people who are younger than 18, have certain medical conditions, or cannot undergo surgery are not eligible. If you join the study, you can expect to be closely monitored before and after your surgery, with a focus on your recovery and quality of life. This trial is currently recruiting participants, and it aims to provide important information that could improve treatment options for patients with back problems in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged ≥ 18 years old
• • Consenting patients undergoing anterior lumbar interbody fusion (ALIF) procedure whom the Conduit cage system is appropriate will be included in this study.
• Exclusion Criteria:
• • Patients under 18 years of age
• • Non-surgical candidates, patients with contraindications to surgery (e.g. medical comorbidities, known infection, pregnancy etc.),
• • Patients with established osteoporosis
• • Long-term, systemic steroid use
• • Systemic diseases (e.g. rheumatoid arthritis, AIDS, HIV, etc.),
• • Patients unwilling or unable to give informed consent, or patients unwilling or unable to complete Health-related quality of (HRQOL) outcome life measures at the specified study time points pre- and post-operatively.
• • Subjects who have a history of drug or alcohol use that, in the opinion of the investigator, would interfere with adherence to study requirements.