Effects of Combined Rectus Sheath and Ilioinguinal Nerve Block on Opioid Consumption in HALDN
Launched by KOÇ UNIVERSITY · Apr 19, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how well two types of regional anesthesia—rectus sheath block and ilioinguinal nerve block—can help manage pain for patients undergoing a specific type of kidney surgery called hand-assisted laparoscopic donor nephrectomy. The main goal is to see if using these nerve blocks can lower the amount of pain medication (opioids) needed after surgery. Researchers also want to find out if using these blocks can help reduce the side effects that sometimes come with opioids and whether it can lead to a shorter hospital stay.
To participate in this trial, you need to be between the ages of 18 and 75 and have been approved by a transplant committee for the kidney donation surgery. You should not have allergies to the medications used in the study or be on long-term narcotics. If eligible, you will be randomly assigned to receive either the nerve blocks or a placebo (a treatment that has no active ingredients) before your surgery. After the procedure, the team will follow up with you for 24 hours to track how much pain medication you use and any side effects you might experience. This study aims to improve pain management and recovery for future kidney donors.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • The donors reviewed by the transplant committee and deemed suitable for nephrectomy.
- • Laparoscopic hand assisted donor nephrectomy operation is planned.
- Exclusion Criteria:
- • Allergy to any of the drugs to be used in treatment
- • Patients using chronic narcotics or narcotic receptor agonists
- • Patients with psychiatric disorders
- • Patients with chronic organ failure
- • Patients without end organ damage
- • The patients who did not give consent
- • Foreign national patients
- • Patients with American Society of Anaesthesiologists (ASA) physical status classification score III and above
About Koç University
Koç University, a leading multidisciplinary research institution located in Istanbul, Turkey, is dedicated to advancing healthcare through innovative clinical research. With a commitment to excellence in education and research, the university fosters collaboration among experts in various fields, aiming to translate scientific discoveries into practical applications that improve patient outcomes. Koç University’s clinical trial initiatives are characterized by rigorous methodologies, ethical standards, and a focus on addressing pressing health challenges, positioning it as a pivotal player in the global research landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Istanbul, Zeytinburnu, Turkey
Patients applied
Trial Officials
Yasemin Sincer, MD
Principal Investigator
Koç University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported