Relationship Between Mouth Opening and Masseter Elasticity in Oral Cancer
Launched by NATIONAL TAIWAN UNIVERSITY HOSPITAL · Apr 15, 2025
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking to understand the relationship between how much patients can open their mouths and the stiffness of a muscle called the masseter, which is important for chewing. Researchers will use a special ultrasound technique to measure the elasticity, or hardness, of this muscle in patients who have recently had surgery for oral cancer. They will also include an exercise program to see if improving the muscle's stiffness can help predict how much better patients will be able to open their mouths, a condition known as trismus, which can affect eating and speaking.
To participate in this study, individuals need to be newly diagnosed with oral cancer and scheduled to receive treatments like surgery or chemotherapy, and they should be between 20 and 65 years old. However, those who cannot communicate or have other movement-related disorders will not be able to join. This trial is not yet recruiting participants, but it aims to provide valuable insights into how muscle stiffness relates to mouth opening after oral cancer treatment.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Newly diagnosed oral cancer patients who are scheduled to receive cancer-related treatments (e.g., oral cancer surgery, radiotherapy, chemotherapy, or chemoradiotherapy).
- • 2. Age between 20 and 65 years.
- Exclusion Criteria:
- • 1. Could not communicate.
- • 2. Had any disorder that could influence movement performance.
About National Taiwan University Hospital
National Taiwan University Hospital (NTUH) is a leading medical institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a pioneer in medical education and patient care in Taiwan, NTUH integrates cutting-edge technology with comprehensive clinical expertise to facilitate groundbreaking studies across various medical fields. The hospital’s dedicated research team collaborates with local and international partners to enhance the understanding of diseases and improve treatment outcomes. By prioritizing patient safety and ethical standards, NTUH strives to contribute to the global medical community and foster advancements in healthcare practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Yueh-Hsia Chen
Principal Investigator
National Taiwan University, College of Medicine
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported