Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Down Syndrome

Launched by RIPHAH INTERNATIONAL UNIVERSITY · Apr 17, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how aerobic exercise affects weight and body fat in children with Down syndrome. Researchers want to find out if combining aerobic exercise with a low-calorie diet helps children lose weight more effectively than just doing exercise alone. The trial will take place over 10 months at a rehab clinic in Lahore and will involve 22 children aged between 8 and 16 years. Participants will be randomly divided into two groups: one group will follow a low-calorie diet along with exercise, while the other group will only do the exercise.

To be eligible for this trial, children should be between 8 and 16 years old, generally healthy, and classified as overweight or obese based on their body mass index (BMI). Parents will need to sign a consent form, and the child's physician must approve their participation. Unfortunately, children with certain medical conditions, previous involvement in weight loss programs, or those on specific diets won't be able to join. Throughout the trial, participants can expect to engage in aerobic exercises like brisk walking, and the researchers will closely monitor their weight and fitness levels. This study aims to provide helpful insights into the best approaches for managing weight in children with Down syndrome.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age (8-16) years.
• • Both Genders (Male and Female).
• • BMI-for-age percentile (at or above 85th percentile is overweight, and at or above 95th percentile is considered as obese)
• • Children with generally stable health condition, without significant co-morbidities that might affect diet or exercise interventions.
• • Consent form signed by parents, along with written approval by the physician.
• Exclusion Criteria:
• • History of any previous medical disease.
• • Previous Participation in any Weight Loss Exercise Program.
• • Participants following any specific diet plan from last 6 months.
• • Exclusion of children on medication that could affect weight or metabolism.
• • Children with physical disabilities that prevent them from safely participating in aerobic exercise.
• • Children with dietary restrictions or food allergies.
• • Children with severe cognitive impairments that prevent them from engaging in exercise program.