Comparison of Outcome of Open Appendectomy With and Without Transversus Abdominis Plane (TAP) Block

Launched by UNIVERSITY OF HEALTH SCIENCES LAHORE · Apr 16, 2025

Keywords

ClinConnect Summary

This clinical trial is studying two different ways to manage pain for patients undergoing an open appendectomy, which is surgery to remove the appendix. One group of patients will receive a special pain relief technique called a Transversus Abdominis Plane (TAP) block, which numbs the abdominal area to help reduce pain after surgery. The other group will have the same surgery but will not receive this TAP block. The goal is to see if using the TAP block can lead to less pain after surgery, shorter hospital stays, fewer complications like nausea and vomiting, and greater overall satisfaction from the patients.

To participate in this study, individuals must be adults aged 18 to 65 who are diagnosed with appendicitis and are fit for general anesthesia. They should have specific symptoms such as pain in the lower right abdomen and possibly fever. However, those with certain conditions, like severe liver disease or who are pregnant, cannot take part. If you do join the trial, you’ll be randomly placed into one of the two groups, and the researchers will follow your recovery to gather important information that could improve pain management for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adults aged 18 to 65 years.
• • Both male and female patients.
• • Patients fit for general anesthesia.
• • Clinical findings of appendicitis.
• • Lower right quadrant or periumbilical pain radiating to the right lower quadrant, with nausea and/or vomiting.
• • Fever \>38°C.
• • Tenderness with Alvarado score \>7.
• Exclusion Criteria:
• • Duration of symptoms \>5 days.
• • Absence of clinical findings of appendicitis.
• • Palpable mass on physical examination suspected for appendiceal abscess.
• • History of cirrhosis or hematological disorders.
• • Allergic to or contraindicated for general anesthesia.
• • Pregnancy.
• • Patients who do not consent to participate.