The Effectiveness, Cost-effectiveness, and Budget Impact of Interventions to Improve the Delivery of Cervical Cancer Screening in Puerto Rico.

Launched by UNIVERSITY OF PUERTO RICO COMPREHENSIVE CANCER CENTER · Apr 16, 2025

Keywords

ClinConnect Summary

Aim 1. Conduct a four-arm multi-site randomized controlled trial to evaluate the effectiveness of three interventions, including patient reminders plus patient navigation and self-collection of HPV test (individually and in combination), compared to patient reminders alone on:

1a. Cervical cancer screening (clinic-based pap test/HPV co-testing) uptake among women and completion of HPV self-collection kit.

1. b. Timely colposcopy and high-grade squamous intraepithelial lesion (HSIL) treatment among women with abnormal screening results. Secondary analyses will examine implementation outcom...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 25-65 years old
• • No history of cervical cancer or hysterectomy
• • Have not had a Pap test in the past 3 years or more, an HPV test in the past 5 years or more, or a combination of a Pap test and an HPV test in the past 5 or more years (co-testing).
• • Must have a record at the study clinics (at least 2 previous visits).
• Exclusion Criteria:
• • Women with no telephone contact information
• • Being pregnant\*
• • Living with HIV, Lupus, or Crohn's\*
• • Active on immunotherapy treatment\*
• • History of organ transplants\*
• • Will be excluded as cervical cancer screening guidelines differ for them.