Fecal DNA Methylation Detection for Gastric Cancer

Launched by FUDAN UNIVERSITY · Apr 22, 2025

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to detect gastric cancer, specifically gastric adenocarcinoma, by examining DNA changes in stool samples. Researchers want to see how well this fecal test works compared to standard imaging tests like CT scans and endoscopy, which are currently used to diagnose this type of cancer.

To participate in the trial, you need to be at least 40 years old and either have or be scheduled for an endoscopy or pathology test. It's important that you can understand and sign the consent form in person. However, people with severe health issues, a history of upper gastrointestinal cancers, pregnant women, or those with certain unspecified conditions cannot join. If you decide to participate, you will provide a stool sample and undergo the usual imaging tests, helping researchers learn more about better ways to detect gastric cancer early.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥40 years, male or female.
• • Have or will have gastroscopy and/or pathology results.
• • No contraindications to endoscopy and able to cooperate with endoscopy.
• • Patients must be able to fully understand the informed consent form and be able to sign the informed consent form in person.
• Exclusion Criteria:
• • Have severe cardiac, hepatic, or renal insufficiency, or mental disorders.
• • Previous history of upper gastrointestinal malignancy.
• • Women during pregnancy.
• • Those with unspecified pathology.