Milk Consumption and Blood Microbiome in Healthy Volunteers

Launched by ERASMUS MEDICAL CENTER · Apr 17, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how drinking milk affects certain bacteria in our intestines and whether these bacteria can be found in the blood. Researchers want to know if the presence of these milk-related bacteria in the blood increases after consuming milk, just like it does in stool samples. To find this out, they will compare blood and stool samples from participants before and after they drink milk for a week.

To participate, you should be between 18 and 65 years old, have a healthy body weight, and not be lactose intolerant. You will need to stop eating any dairy for ten days and then drink milk every day for a week. During the study, you’ll provide blood and stool samples at different times to help researchers gather the necessary information. It’s important to note that certain health conditions, medications, and lifestyle choices may exclude you from participating. If you’re interested, this study offers a chance to contribute to understanding how our diets can impact our health!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age 18-65 years
• • 18.5 =\< BMI \< 25 kg/m2
• • All genders included
• • Not be lactose intolerant
• • Willing to consume milk
• Exclusion Criteria:
• • Regularly used medications such as antibiotics, steroids, beta blockers, and adrenergic- stimulating agents (self-report)
• • Regular use of prebiotic and/or probiotics apart from yogurt and young soft cheese (self-report)
• • Antibiotic intake in the previous months (self-report)
• • Daily consumption of more than 10 cigarettes (self-report)
• • Chronic diseases including type 2 diabetes, hypertension, fatty liver disease, cancer, or autoimmune disease (self-report)
• • Internal diseases, including those of the gastrointestinal tract, lung, heart, vasculature, liver, and kidney (self-report)
• • Eating disorder or unconventional eating habits (self-report)
• • Participation in another study (self-report)
• • Women: pregnancy and breastfeeding (self-report)