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Search / Trial NCT06946030

Pseudoexfoliation and Carpal Tunnel Study

Launched by ANKARA TRAINING AND RESEARCH HOSPITAL · Apr 19, 2025

Trial Information

Current as of October 02, 2025

Enrolling by invitation

Keywords

Carpal Tunnel Syndrome (Cts) Pseudoexfoliation Syndrome Biochemical Marker

ClinConnect Summary

This study, called the Pseudoexfoliation and Carpal Tunnel Study, is an observational, prospective case-control project at Ankara Training and Research Hospital. Researchers want to learn how often eye-related pseudoexfoliation syndrome (PES) and carpal tunnel syndrome (CTS) occur together and whether they share underlying biological factors. They will test nerve function with electromyography (EMG) and, if CTS is found, ask participants to complete a short CTS symptom and daily function questionnaire (the Boston Carpal Tunnel Questionnaire). They may also look at biochemical markers to understand any links between PES and CTS. The study does not test a treatment.

If you are eligible, you could join one of two groups. PES participants will be adults 18–90 diagnosed with PES during a routine eye exam and will have an EMG test on the same day to check for CTS. A comparison group will include adults of similar age and sex who have mechanical pain in the back, knee, or hip but no CTS symptoms, who will also have an EMG test on the same day. Exclusions include major hand-wrist trauma or surgery, diabetes, rheumatoid or thyroid disease, pregnancy, and several other conditions. The researchers will collect basic health information and EMG results from both groups. The study aims to enroll about 118 people and results will be shared in aggregated form to protect individual privacy.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Being between the ages of 18-90
  • Having been diagnosed with PES during routine eye examination
  • Exclusion Criteria:
  • History of major hand-wrist trauma or surgical intervention
  • Acromegaly
  • Presence of any structural abnormality in bone structure
  • Pregnancy
  • Diabetes mellitus
  • Gout
  • Rheumatoid arthritis
  • Connective tissue disease
  • Acromegaly
  • Thoracic outlet syndrome
  • Brachial plexopathy
  • Cervical disc herniation
  • Presence of cardiac pacemaker
  • Steroid users
  • Thyroid disease
  • Repetitive hand operations

About Ankara Training And Research Hospital

Ankara Training and Research Hospital is a leading medical institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital is committed to enhancing patient outcomes by exploring new therapies and medical interventions across a variety of disciplines. With state-of-the-art facilities and a multidisciplinary team of experienced professionals, Ankara Training and Research Hospital prioritizes patient safety and ethical standards while contributing to the global body of medical knowledge. Their collaborative approach fosters partnerships with academic institutions and industry stakeholders, ensuring rigorous research methodologies and the effective translation of findings into clinical practice.

Locations

Ankara, Altindag, Turkey

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported