Pseudoexfoliation and Carpal Tunnel Study
Launched by ANKARA TRAINING AND RESEARCH HOSPITAL · Apr 19, 2025
Trial Information
Current as of October 22, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This study, called the Pseudoexfoliation and Carpal Tunnel Study, is an observational, prospective case-control project at Ankara Training and Research Hospital. Researchers want to learn how often eye-related pseudoexfoliation syndrome (PES) and carpal tunnel syndrome (CTS) occur together and whether they share underlying biological factors. They will test nerve function with electromyography (EMG) and, if CTS is found, ask participants to complete a short CTS symptom and daily function questionnaire (the Boston Carpal Tunnel Questionnaire). They may also look at biochemical markers to understand any links between PES and CTS. The study does not test a treatment.
If you are eligible, you could join one of two groups. PES participants will be adults 18–90 diagnosed with PES during a routine eye exam and will have an EMG test on the same day to check for CTS. A comparison group will include adults of similar age and sex who have mechanical pain in the back, knee, or hip but no CTS symptoms, who will also have an EMG test on the same day. Exclusions include major hand-wrist trauma or surgery, diabetes, rheumatoid or thyroid disease, pregnancy, and several other conditions. The researchers will collect basic health information and EMG results from both groups. The study aims to enroll about 118 people and results will be shared in aggregated form to protect individual privacy.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Being between the ages of 18-90
- • Having been diagnosed with PES during routine eye examination
- Exclusion Criteria:
- • History of major hand-wrist trauma or surgical intervention
- • Acromegaly
- • Presence of any structural abnormality in bone structure
- • Pregnancy
- • Diabetes mellitus
- • Gout
- • Rheumatoid arthritis
- • Connective tissue disease
- • Acromegaly
- • Thoracic outlet syndrome
- • Brachial plexopathy
- • Cervical disc herniation
- • Presence of cardiac pacemaker
- • Steroid users
- • Thyroid disease
- • Repetitive hand operations
About Ankara Training And Research Hospital
Ankara Training and Research Hospital is a leading medical institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital is committed to enhancing patient outcomes by exploring new therapies and medical interventions across a variety of disciplines. With state-of-the-art facilities and a multidisciplinary team of experienced professionals, Ankara Training and Research Hospital prioritizes patient safety and ethical standards while contributing to the global body of medical knowledge. Their collaborative approach fosters partnerships with academic institutions and industry stakeholders, ensuring rigorous research methodologies and the effective translation of findings into clinical practice.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, Altindag, Turkey
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported