Assessing the Time-Course of Dexmedetomidine-Induced Analgesia Via EEG

Launched by CHINA INTERNATIONAL NEUROSCIENCE INSTITUTION · Apr 23, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how a medication called dexmedetomidine affects pain relief in patients undergoing total hip replacement surgery. The goal is to understand how quickly and effectively this medication works in the brain by using a method called EEG, which measures brain activity. Patients who are scheduled for this surgery and meet certain criteria will receive dexmedetomidine just before and during the procedure to see how it helps with pain and other side effects after surgery.

To be eligible for the trial, participants need to be between 18 and 70 years old, have hip osteoarthritis, and be in good overall health based on specific medical guidelines. Throughout the study, patients will be monitored for their pain levels, any nausea or dizziness, and how quickly their digestive system starts working again after surgery. It's important to note that this trial is not yet recruiting participants, so those interested should keep an eye out for updates.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with hip osteoarthritis scheduled for total hip arthroplasty under intrathecal anesthesia; Age 18-70 years; American Society of Anesthesiologists (ASA) physical status classification I-III; Body mass index (BMI) 22-30 kg/m².
• Exclusion Criteria:
• • Pre-existing peripheral or central nervous system disorders; Mental disorders; Cognitive impairment; Emergency surgery; or Hearing impairment.