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Search / Trial NCT06946329

WATERinMOTION Aquatic Therapy in Obese Men With Knee Osteoarthritis

Launched by UNIVERSITY OF SISTAN AND BALUCHESTAN · Apr 19, 2025

Trial Information

Current as of July 25, 2025

Enrolling by invitation

Keywords

Aquatic Therapy Exercise Therapy Quality Of Life Biomarkers Wearable Electronic Devices

ClinConnect Summary

100 participants (BMI ≥30, age 45-65, radiographic knee OA) will be randomized to:

Aquatic group: 24 sessions over 8 weeks (3x/week) in 32°C water, progressing from buoyancy-assisted to resistance exercises.

Land group: Matched duration/intensity land-based rehabilitation. Primary outcomes: WOMAC pain/function. Secondary outcomes: SF-36 quality of life, serum COMP, 6-minute walk test, and accelerometer-measured step count.

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • Males aged 45-65
  • BMI ≥30 kg/m²
  • Radiographic knee OA (Kellgren-Lawrence grade 2-3)
  • WOMAC pain score ≥25/50
  • Exclusion Criteria:
  • Inflammatory arthritis (e.g., rheumatoid)
  • Intra-articular injections within 3 months
  • Contraindications to aquatic exercise

About University Of Sistan And Baluchestan

The University of Sistan and Baluchestan is a prestigious academic institution committed to advancing research and education in the fields of health sciences and medicine. With a focus on innovative clinical research, the university aims to contribute to the development of evidence-based practices and improve patient outcomes. Through collaboration with local and international partners, the university fosters a multidisciplinary approach to clinical trials, ensuring rigorous methodologies and ethical standards are upheld. Its dedication to scientific excellence positions the University of Sistan and Baluchestan as a key player in the advancement of healthcare research in the region.

Locations

Zahedan, Sistan And Baluchestan, Iran, Islamic Republic Of

Patients applied

0 patients applied

Trial Officials

Mohammadreza Rezaeipour, MD,PhD

Study Director

Assoc.Prof.Dr. of University of Sistan and Baluchestan, Zahedan, Iran

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported