First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis.

Launched by NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS · Apr 20, 2025

Keywords

ClinConnect Summary

This clinical trial is investigating a new way to diagnose pleural effusion, which is a buildup of fluid in the space around the lungs. The study specifically looks at patients who may have cancer-related fluid in this area. It compares a new method called Local Anesthesia Thoracoscopy (LAT) with standard diagnostic methods. LAT allows doctors to take a tissue sample directly from the pleural space while the patient is awake and comfortable. The trial aims to see how well this new method works, how quickly it helps make a diagnosis, and how safe and comfortable it is for patients.

To participate in the trial, patients must be between the ages of 65 and 74 and have an undiagnosed pleural effusion that has certain characteristics. However, some patients may not be eligible if they have certain conditions, like infections in the pleural space or severe breathing difficulties. If someone joins the trial, they can expect to undergo the LAT procedure and be closely monitored for its effectiveness and their comfort during the process. This research could help improve how doctors diagnose and treat pleural effusion in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Undiagnosed pleural effusion with the character of a lymphocytic exudate
• Exclusion Criteria:
• • Empyema
• • Transudate pleural effusion.
• • Central airway obstruction by tumor.
• • Existence of extensive adhesions that do not allow the development of iatrogenic pneumothorax and the safe entry of the thoracoscope.
• • Uncontrollable cough.
• • Acute respiratory failure and/or Hypercapnia.
• • Performance Status: 5