Misoprostol Before Caesarean Section

Launched by KAFRELSHEIKH UNIVERSITY · Apr 25, 2025

Keywords

ClinConnect Summary

This clinical trial is studying the use of a medication called Misoprostol, given before a planned (elective) cesarean section, to see if it helps prevent breathing problems in newborns. The focus is on pregnant women who are less than 38 weeks along in their pregnancy and are scheduled for a C-section. The goal is to find out if this treatment can reduce the chances of respiratory issues for babies born under these circumstances.

To be eligible for the trial, women should be under 35 years old, have a singleton pregnancy (meaning they are having one baby), and have a confirmed gestational age of less than 38 weeks. However, women with certain health issues, like high blood pressure or diabetes, or those who have had two or more previous C-sections will not be able to participate. If you join the trial, you can expect to receive the Misoprostol medication before your scheduled C-section and be closely monitored for safety and effectiveness. This study is currently recruiting participants, and it's important to discuss any questions or concerns with your healthcare provider.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Women with indication for elective caesarean section.
• • Age less than 35 years old.
• • Gestational age less than 38 weeks.
• • Gestational age will be confirmed by certain LMP or reliable early ultrasound measurement of crown-rump length.
• • Singleton pregnancy with no major anomalies
• Exclusion Criteria:
• • Any obstetric disorders as preeclampsia and diabetes.
• • Fetus with oligohydramnios, intrauterine growth restriction.
• • Any contraindications to misoprostol like those with previous allergic reaction or hypersensitivity to prostaglandin hemorrhagic disorders, and severe anemia.
• • History of more than or equal 2 previous caesarean section.