Role of Frozen Section in Categorization of Thyroid Follicular Neoplasm

Launched by ASSIUT UNIVERSITY · Apr 19, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how effective a method called "frozen section" is in determining whether a type of thyroid tumor, known as a follicular neoplasm, is benign (not cancerous) or malignant (cancerous). By accurately distinguishing between these two types, the goal is to help prevent unnecessary surgeries for patients who have benign tumors. Researchers will compare the results from frozen sections, which are quick tests done during surgery, with results from standard tests on samples that take longer to prepare.

To participate in this study, individuals must have a thyroid nodule that has been diagnosed as a "follicular neoplasm" through a fine needle aspiration, which is a procedure that uses a thin needle to take a sample of tissue. Those who have been diagnosed with non-cancerous conditions or other types of thyroid cancer will not be eligible. Participants can expect to undergo a surgery called hemi-thyroidectomy, where half of the thyroid gland is removed, and their test results will be closely monitored to see how well the frozen section method works. The trial is not yet recruiting participants, so there will be more information available soon.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Cases presented with a thyroid nodule, diagnosed as "follicular neoplasm" (Bethesda category IV) by fine needle aspiration cytology, and underwent hemi-thyroidectomy.
• Exclusion Criteria:
• • Cases with thyroid nodule and diagnosed by fine needle aspiration cytology as non-neoplastic lesions, suspicious for malignancy or as malignant.