Optimizing High Flow Nasal Cannula Oxygenation in Pediatric Airway Procedures
Launched by THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER, HOUSTON · Apr 24, 2025
Trial Information
Current as of July 27, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how to improve oxygen delivery during certain airway procedures in children, specifically laryngoscopy and bronchoscopy. The researchers want to find out whether using a higher or lower flow rate of oxygen can help keep kids from having low oxygen levels during these procedures and how it affects the amount of carbon dioxide in their blood.
To be a part of this study, children must be scheduled for these specific procedures at Children's Memorial Hermann Hospital, weigh at least 5 kilograms, and will be using oxygen flow rates between 5 to 45 liters per minute. However, kids in emergency situations or with certain medical conditions, like tracheostomy or heart defects, won't be eligible to participate. If your child qualifies and takes part, they will have their oxygen and carbon dioxide levels monitored during the procedure to see which method works best for keeping them safe and comfortable. The study is not yet recruiting participants, so there will be more information available soon for families interested in this research.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • undergoing laryngoscopy and bronchoscopy procedures at Children's Memorial Hermann Hospital (CMHH)
- • weight greater than or equal to 5 kilograms and using flow rates between 5 to 45 liters per minute (BTPS)
- Exclusion Criteria:
- • Emergency type cases, tracheostomy patients, unrepaired cyanotic heart disease, nasal deformity/choanal atresia, or cautery/laser type procedures
About The University Of Texas Health Science Center, Houston
The University of Texas Health Science Center at Houston (UTHealth) is a leading academic institution dedicated to advancing health through education, research, and clinical practice. As a prominent sponsor of clinical trials, UTHealth leverages its extensive resources and expertise in biomedical research to facilitate innovative studies aimed at improving patient outcomes. The institution is committed to fostering a collaborative environment that promotes scientific discovery and the translation of research findings into effective healthcare solutions, all while adhering to the highest ethical standards and regulatory guidelines. With a multidisciplinary approach, UTHealth plays a critical role in addressing complex health challenges and enhancing the quality of life in diverse communities.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Houston, Texas, United States
Patients applied
Trial Officials
Zhen Huang, MD
Principal Investigator
The University of Texas Health Science Center, Houston
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported