Evaluation of Moringa Oleifera Leaf Extract Versus Sodium Hypochlorite in Pulpectomy of Nonvital Primary Molars
Launched by CAIRO UNIVERSITY · Apr 24, 2025
Trial Information
Current as of July 27, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effectiveness of Moringa Oleifera leaf extract compared to Sodium Hypochlorite in treating nonvital primary molars in children aged 3 to 7 years. Nonvital primary molars are baby teeth that have become infected or damaged, and the trial aims to see which treatment helps heal the tooth better over a period of 12 months. Researchers will look at signs like pain, swelling, and tooth movement, as well as take X-rays to check if the tooth is healing properly.
To be eligible for the trial, children must be between 3 and 7 years old, able to cooperate during treatment, and have specific dental issues that require a pulpectomy (a procedure to clean out the infected tooth). However, children with certain health problems, teeth that are too damaged, or those who have had previous treatments on the tooth will not be included. If your child qualifies and participates, they will receive one of the two treatments and will be monitored for any changes in their condition over the year.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Cooperative children aged between 3-7 years
- • Males/Females.
- • Primary molars necessitating pulpectomy diagnosed with deep dental caries with pulp necrosis and periapical pathosis or both.
- • Systemically healthy children
- Exclusion Criteria:
- • Medically compromised and uncooperative children
- • Tooth indicated for extraction due to root resorption more than two thirds of the root, teeth near exfoliation, deep subgingival caries hindering proper coronal seal.
- • Mobile teeth (Miller's Grade 2 or more)
- • Previous pulp therapy
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
El Manial, Giza, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported