Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Fibromyalgia.

Launched by SULTAN ABDULHAMID HAN TRAINING AND RESEARCH HOSPITAL, ISTANBUL, TURKEY · Apr 21, 2025

Keywords

ClinConnect Summary

This clinical trial is looking into how certain symptoms related to central sensitization, which is when the nervous system becomes overly sensitive, affect thinking and memory problems in people with fibromyalgia. Researchers want to understand if these symptoms make it harder for fibromyalgia patients to think clearly and how these thinking issues relate to the overall severity of their condition.

To participate, individuals need to be between 18 and 65 years old and have a confirmed diagnosis of fibromyalgia. They also need to be able to read and agree to join the study. If someone has other serious health conditions, such as infections or diseases affecting the brain, or if they are outside the age range, they won’t be eligible. Participants will be asked to share their experiences and may undergo assessments to help researchers understand how fibromyalgia impacts both physical and mental health. This study is currently recruiting participants, and it aims to shed light on the connection between physical symptoms and cognitive challenges in fibromyalgia.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Being diagnosed with fibromyalgia according to American College of Rheumatology 2016 criteria
• • Being between 18-65 years old
• • Being literate
• • Accepting to participate in the study
• Exclusion Criteria:
• • Concomitant systemic inflammatory disease, central nervous system disease (cortical involvement), active infection and malignancy history
• • History of illness that may lead to cognitive impairment
• • Being \<18 and \>65 years old
• • Being illiterate
• • Not accepting to participate in the study