Exercise Capacity, Muscle Oxygenation, and Physical Activity Between Patients With Interstitial Lung Disease

Launched by GAZI UNIVERSITY · Apr 22, 2025

Keywords

ClinConnect Summary

This clinical trial is studying how exercise capacity, muscle oxygen levels, and physical activity differ between patients with interstitial lung disease (ILD) and healthy individuals. ILD is a group of chronic lung conditions that can make it hard to breathe and impact overall health. The researchers want to understand how these factors, along with respiratory function and quality of life, compare in people with ILD versus those who are healthy. This is important because it could help improve care and support for patients with lung diseases.

To participate, patients with ILD need to be between 18 and 75 years old and diagnosed according to specific guidelines. They should not have had a recent lung infection or be dealing with certain serious health conditions. Healthy participants should be between 45 and 80 years old, with no chronic diseases. Everyone involved will undergo tests to evaluate their exercise capacity and other health measures. This study is currently recruiting participants, and it aims to provide valuable insights into how ILD affects physical abilities and overall well-being.

Gender

ALL

Eligibility criteria

• • Patients who will participate in the study;
• Inclusion Criteria:
• • Patients diagnosed with ILD according to ATS/ERS criteria,
• • Ages between 18 and 75,
• • Pulmonary infection during the previous month,
• • Participants who voluntarily participated in the study were included.
• Exclusion Criteria:
• * Patients were excluded if they had:
• • Acute pulmonary exacerbation or respiratory infection in the last four weeks
• • Obstructive lung disease
• • Systemic conditions affecting neurological, neuromuscular, orthopedic, or physical functions
• • Recent participation in a planned exercise program (within three months)
• • Cognitive impairment affecting exercise test understanding
• • Contraindications to exercise testing per the American Sports Medicine Association
• • Cancer, renal, or hepatic disease
• • Aortic stenosis, complex arrhythmia, or aortic aneurysm
• • Serious cardiovascular diseases like uncontrolled hypertension, diabetes, heart failure, or arrhythmia
• • For healthy individuals who will participate in the study;
• Inclusion Criteria:
• • No diagnosed chronic disease,
• • Healthy adults between the ages of 45-80
• Exclusion Criteria:
• • Individuals with a Mini Mental State Assessment Scale score of less than 24,
• • A smoking history of at least 10 packs×years or more,
• • Having had COVID-19,
• • A BMI of \>30 kg/m2