The Effect of Supplementation With Fish Oil (EPAX EVOLVE 05) on Sperm Quality
Launched by EPAX NORWAY AS · Apr 22, 2025
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at whether taking fish oil can improve sperm quality in healthy men who currently have poor sperm quality. Men who are between the ages of 18 and 55 and have been told they have low sperm motility (meaning their sperm doesn’t move well) may be eligible to participate. Participants will need to be okay with not having any sexual activity for at least two days before providing a sperm sample for testing. They will be asked to take either a fish oil capsule or a placebo (which has no active ingredients) twice a day for three months.
During the trial, participants will provide sperm samples at the beginning and end of the study to see if their sperm quality has improved. It's important for potential participants to know that they cannot take any omega-3 supplements or cod liver oil during the study but can use other vitamins or supplements. Certain health conditions or allergies, such as a known allergy to fish or specific reproductive issues, may disqualify individuals from joining the study. This trial is an opportunity to explore how a common supplement might help with sperm health.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Men aged 18-55
- • 2. Referred for or claiming a semen analysis.
- • 3. Willing to have at least 2 days abstinence of sexual activity prior to a sperm sample being taken.
- 4. Reduced semen quality defined as:
- • • Progressive motility: \<30%
- • 5. Willing to refrain from omega-3/cod liver oil supplementation during the study. Use of other supplements is allowed.
- • -
- Exclusion Criteria:
- • 1. Known allergy to fish products
- • 2. Historically, known, or suspected bacterial infection in reproductive organs
- • 3. Varicocele suspected from physical examination
- • 4. Azoospermia
- • 5. Diagnosis of diabetes (type 2)
- • 6. Diagnosis of Crohn´s Disease
- • 7. Inferior semen quality due to medical reasons, such as cryptorchidism (via questionnaire/medical records) -
About Epax Norway As
Epax Norway AS is a leading biotechnology company specializing in the development and production of high-quality omega-3 fatty acids for pharmaceutical and nutraceutical applications. With a strong commitment to scientific research and innovation, Epax focuses on the extraction and purification of omega-3s from marine sources, ensuring sustainability and environmental responsibility. The company aims to enhance health and well-being through its products, which are backed by rigorous clinical trials and regulatory compliance. By collaborating with healthcare professionals and researchers, Epax strives to deliver effective solutions that meet the evolving needs of the health market.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Oslo, , Norway
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported