ESCAPE : Evaluation of Spinal Conservation by Endoscopic Procedures to Avoid Fusion

Launched by UNIVERSITY HOSPITAL, BORDEAUX · Apr 22, 2025

Keywords

ClinConnect Summary

The ESCAPE trial is studying a new type of surgery called endoscopic surgery for patients with spinal conditions like spinal stenosis (narrowing of the spine) and spondylolisthesis (when one vertebra slips over another). This method aims to relieve pressure on the spine without the need for more invasive procedures, which can help keep the spine stable and functioning well. The main goal of the research is to see if using endoscopic techniques can reduce the need for traditional spinal fusion surgery, which is when two or more bones in the spine are permanently joined together.

To join this trial, participants need to be at least 18 years old and have specific spinal issues that require surgery. This includes conditions related to previous spinal surgeries, herniated discs, or degenerative conditions causing slippage of the vertebrae. Individuals who are under legal guardianship, in prison, or unable to give consent cannot participate. Those who take part can expect to undergo a less invasive surgery, which may lead to quicker recovery times and less pain compared to traditional methods. This trial is currently recruiting participants, and it could offer a promising alternative treatment for those with challenging spinal conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient ≥ 18 years old
• * Patient consulting for a medical reason involving a spinal pathology in the investigating center :
• • Syndrome adjacent to an old lumbar arthrodesis defined on preoperative radiographs by an antero-posterior translation \> 3 mm, segmental kyphosis \> 10° or a disc height reduced by more than 50%, or on preoperative MRI by central stenosis of grade C or D of the Schizas classification or a herniated disc Grade 1 or 2 degenerative spondylolisthesis, i.e. with slippage less than 50% of the depth of the underlying vertebral body.
• • Lumbar stenosis complicating lumbar scoliosis defined by a deformation with rotation of the vertebral bodies on a frontal radiograph (absence of centering of the spinous process between the two pedicles of the vertebra concerned) and a Cobb angle greater than 20° or a rotational dislocation .
• • - Indication for spinal surgery by endoscopy
• Exclusion Criteria:
• • Patient under guardianship or curatorship,
• • Persons deprived of liberty by judicial or administrative decision,
• • Persons undergoing psychiatric treatment under duress requiring the consent of the legal representative
• • Persons unable to express their consent,
• • Persons under legal protection,
• • Patient not affiliated to a social protection scheme.