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Search / Trial NCT06950931

Posttranslationally Modified Fetuin-A in Urine as a Marker for Renal Dysfunction (Patients With Chronic Kidney Disease - With or Without Kidney Transplantation).

Launched by UNIVERSITY HOSPITAL, MARTIN · Apr 22, 2025

Trial Information

Current as of June 26, 2025

Enrolling by invitation

Keywords

Kidney Transplant Recipient Urinary Post Translationally Modified Fetuin A Graft Failure Acute Kidney Injury Biopsy Of Native Kidney

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria for patients with kidney transplatation:
  • patient age \> 18 years,
  • primary kidney transplantation;
  • at least 12 months after kidney transplantation;
  • immunosuppression: calcineurin inhibitors, mycophenolic acid analogues and corticosteroids;
  • living donor or donation after brain death (DBD) donor;
  • patient cooperation;
  • regular check-ups in Transplant-Nephrology surgery at University Hospital Martin;
  • provision of a sample of the first-morning urine;
  • signed informed consent.
  • Exclusion Criteria with kidney transplatation:
  • • patient age \< 18 years;
  • secondary/tertiary kidney transplantation;
  • kidney transplantation in the last 12 months;
  • absence of ≥1 of the basic immunosuppressants (calcineurin inhibitors, mycophenolic acid analogues and corticosteroids);
  • contaminated sample of the first-morning urine (for example, menstruation);
  • non-provision of a sample of the first-morning urine;
  • disagreement of the patient with the Examination and inclusion in the study.
  • Inclusion Criteria for patients without kidney transplatation:
  • patient age \> 18 years,
  • chronic kidney injury or acute kidney injury
  • performed renal biopsy
  • patient cooperation;
  • regular check-ups in Transplant-Nephrology surgery at University Hospital Martin;
  • provision of a sample of the first-morning urine;
  • signed informed consent.
  • Exclusion Criteria with kidney transplatation:
  • patient age \< 18 years;
  • absence of renal biopsy or non-represenantative sample of renal biopsy
  • contaminated sample of the first-morning urine (for example, menstruation);
  • non-provision of a sample of the first-morning urine;
  • disagreement of the patient with the Examination and inclusion in the study.

About University Hospital, Martin

University Hospital Martin is a leading academic medical center dedicated to advancing healthcare through innovative research and clinical trials. With a commitment to patient-centered care and cutting-edge medical practices, the hospital collaborates with a diverse array of researchers and healthcare professionals to explore new therapeutic approaches and improve patient outcomes. Its state-of-the-art facilities and multidisciplinary teams enable the rigorous evaluation of novel treatments, contributing to the global body of medical knowledge while enhancing the quality of care provided to the community.

Locations

Martin, , Slovakia

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported