Hematological Markers in Idiopathic Carpal Tunnel Syndrome
Launched by ANKARA TRAINING AND RESEARCH HOSPITAL · Apr 29, 2025
Trial Information
Current as of September 12, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
This study is looking at whether people with idiopathic Carpal Tunnel Syndrome (CTS) have higher signs of inflammation in their blood and different vitamin B12 levels compared with healthy people. Researchers will compare CTS patients who had EMG testing to healthy controls of the same age and sex. They will check several blood markers that scientists think reflect inflammation (things like SIRI, NLR, PLR, MLR, and SII) as well as C‑reactive protein (CRP) and vitamin B12, and they will look at how severe CTS appears on EMG tests. The goal is to understand if chronic inflammation or low vitamin B12 might be related to CTS.
Who can be eligible? Adults aged 18 to 65 who were tested with EMG for CTS-like symptoms and have recent blood test results (a complete blood count, CRP, and vitamin B12) available. The study also includes healthy volunteers who are matched by age and sex and do not have CTS. Exclusion criteria include pregnancy, diabetes, kidney disease, gout, rheumatoid or thyroid problems, nerve or neck conditions, wrist injury or surgery, and several other medical issues. This is an observational, case‑control study conducted at Ankara Training and Research Hospital, led by Nadide Koca, and it involves reviewing past records rather than giving a new treatment. No individual data will be shared publicly. The study is expected to enroll through 2025 and isn’t a test of a therapy itself.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age between 18-65 years
- • Having undergone Electromyography (EMG) testing for Carpal Tunnel Syndrome (CTS)-like symptoms
- • Recent complete blood count, C-Reactive Protein (CRP), and vitamin B12 tests available
- Exclusion Criteria:
- • Age below 18 or above 65 years
- • Pregnancy
- • History of wrist trauma or surgical operation
- • Diabetes mellitus
- • Chronic kidney disease
- • Gout
- • Rheumatoid arthritis
- • Connective tissue disease
- • Thyroid disorders
- • Acromegaly
- • Polyneuropathy
- • Thoracic outlet syndrome
- • Brachial plexopathy
- • Cervical disc herniation
- • Presence of cardiac pacemaker
- • Steroid use
About Ankara Training And Research Hospital
Ankara Training and Research Hospital is a leading medical institution dedicated to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital is committed to enhancing patient outcomes by exploring new therapies and medical interventions across a variety of disciplines. With state-of-the-art facilities and a multidisciplinary team of experienced professionals, Ankara Training and Research Hospital prioritizes patient safety and ethical standards while contributing to the global body of medical knowledge. Their collaborative approach fosters partnerships with academic institutions and industry stakeholders, ensuring rigorous research methodologies and the effective translation of findings into clinical practice.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ankara, Altindag, Turkey
Patients applied
Trial Officials
Nadide Koca, M.D.
Principal Investigator
University of Health Sciences, Ankara Training and Research Hospital, TURKEY
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported